The Piper Comanche plane, registered as PT-DKA, took off Thursday morning from a private airport in the city of Sao Paulo, with two people on board, the authorities said, Xinhua news agency reported.
The Brazilian Air Force said its experts were determining the cause of the crash.
The accident occurred in a mountainous tropical forest area, where a helicopter heading to the island of Ilhabela crashed last December, killing four.
